presented several early adopter case studies in Singapore with a focus on PPVC.
Greater public awareness may help to reduce some of this wastage through a reduction in demand..Looking forward, there is a growing dilemma that new modalities may increase the diversity of solvents – acetonitrile, for example, may be of particular concern.
The good news is that there is already some strategic collaboration happening in these areas.. As many new medicines are developed by start-ups, if we can ensure good guidance and information then we can get things right from the start.There are already collaborative groupings of start-ups, and linking these with the information flow on alternatives and economics could be highly beneficial..The group agreed that framing the driver for change around waste reduction and sustainable economics, together with greater public and business awareness and, would help to push the agenda in the right direction.. Regulators and regulations can be enablers for change, rather than inertial.
The more consistent and proactive enablers, the better; they could create an environment where positive change can happen quickly within a clear, consistent economic playing field.. New technologies, including AI models to help predict the presence of harmful impurities alongside developments in impurity detection at parts per trillion levels, could be extremely useful.In conjunction with testing/development facilities, these technologies could accelerate problem finding and solving..
Fear, and the inertia of uncertainty, is lessened by shining a light on the technological and economic opportunities.
This includes sharing insights from the R&D-led industry with contract manufacturers, generics and start-ups..Instead of approaching this task as thousands of individual refurbishments, we need to have a unified approach where the design is simplified and standardised in such a way that a much wider range of designers, manufacturers and contractors can participate, and the design knowledge is embedded in building systems and design tools so that everyone involved can benefit from the learning on all the other projects.. To achieve this, we are working with Terra Praxis and their wider team, including specialists from MIT, University at Buffalo, Microsoft and KPMG, to:.
Reduce, rationalise, standardise and optimise the building and engineering systems that are needed for a refurbished plant, in order to.Reduce, rationalise, standardise and optimise the design, approval, manufacture, assembly and operation processes, in order to.
Reduce, rationalise, standardise and optimise the interactions between the required different supply chain organisations, to realise the processes described above at the scale that is required.. Terra Praxis are creating a business model that uses technology to connect people, organisations, and resources in an interactive ecosystem in which value can be created and exchanged.To realise this ecosystem, Bryden Wood is involved in developing a technological infrastructure that provides tools and services that make it easy for customers and suppliers to interact to realise the required refurbishments.. To make that possible, Bryden Wood also need to create an engineering platform solution: a building system that can deliver the required variety of solutions for differing requirements in different situations, but that is rationalised, standardised and optimised appropriately to enable the required simplification of all processes that make it possible for the supply chain to collaboratively deliver this built solution.. New nuclear: system simplification and standardisation with P-DfMA.
(Editor: Heavyweight Raincoats)